Seishin Shin Hospital is located in the alley of Kabukicho. Due to the local situation, most of the patients who come to the emergency room are poor wanderers, foreigners, cowherds, young ladies, etc. Different from ordinary hospitals, patients with special backgrounds.At this moment, a mysterious woman, Yoko Nishi Freeman (played by Eiko Koike), a former American military doctor, suddenly arrived.Then, the gears start turning when Takano Hyoge (Nakano Taiga), a cosmetic dermatologist who works at the hospital of her elderly uncle, meets her.